The sisters in South Sudan render various humanitarian services for the upliftment of the poor and marginalised. The main apostolate is care of the sick in the hospital, where they attend to an average of 150 patients daily. They are also engaged in pastoral and educational ministries of the mission in the villages. Programmes and seminars are organised in different sectors for various groups: Alter servers, Alleluia Dancers and Daughters of Mary assist in carrying out the activities of the mission.